Name | Chloroquine diphosphate |
Synonyms | Arechin 3377 RP Avloclor Alermine AI3-14952 UNII-6E17K3343P Aralen phosphate Aralen diphosphate chloroquin Phosphate Chloroquine phosphate Chlorochin diphosphate Chloroquine diphosphate dl-Chloroquine diphosphate Chloroquine bis(phosphate) 7-Chlor-4-(4-diaethylamino)-1-methylbutylamino)-chinolindiphosphat Quinoline, 7-chloro-4-(4-diethylamino-1-methyl-butylamino)-, diphosphate |
CAS | 50-63-5 6384-82-3 69698-56-2 |
EINECS | 200-055-2 |
InChI | InChI=1/C18H26ClN3.2H3O4P/c1-4-22(5-2)12-6-7-14(3)21-17-10-11-20-18-13-15(19)8-9-16(17)18;2*1-5(2,3)4/h8-11,13-14H,4-7,12H2,1-3H3,(H,20,21);2*(H3,1,2,3,4) |
Molecular Formula | C18H26ClN3· 2H3PO4 |
Melting Point | 200℃ |
Boling Point | 460.6°C at 760 mmHg |
Flash Point | 232.3°C |
Solubility | DMSO <1 mg/mL ;Water 100 mg/mL;Ethanol <1 mg/mL. Easily soluble in water (1% aqueous solution has a pH of about 4.5, and less soluble when neutral or alkaline). Almost insoluble in ethanol, benzene, chloroform and ether. |
Vapor Presure | 1.15E-08mmHg at 25°C |
Appearance | powder or crystals |
Storage Condition | 2-8℃ |
Sensitive | Sensitive to light |
MDL | MFCD00069852 |
Physical and Chemical Properties | Melting Point: 200°C |
Use | Antimalarial and anti-amoebic drugs for the control of malaria pathologies, control prevention of malaria symptoms and amebic liver abscess |
Hazard Symbols | Xn - Harmful |
Risk Codes | R22 - Harmful if swallowed |
Safety Description | S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. |
Reference Show more | 1. [IF=3.361] Lancheng Wang et al."Using dual exonucleases to finely distinguish structural adjustment of aptamers for small-molecule detection."Rsc Adv. 2021 Oct;11(52):32898-32903 |